The role of diet in preventing hypertension and cardiovascular diseases in African Americans, who have a much higher risk of developing these diseases, is not well understood. Therefore, this project will investigate whether African Americans following a 100% plant-based diet have more optimal blood pressure, vascular function, and blood lipid profiles, along with lower systemic inflammation relative to African Americans following a typical American diet.
Study Type
OBSERVATIONAL
Enrollment
19
Participants self-reported adherence to a typical American diet prior to enrolling in the study. This factor determined cross-sectional group allocation.
Participants self-reported adherence to a 100% plant-based diet prior to enrolling in the study. This factor determined cross-sectional group allocation.
UT Arlington - Science and Engineering Innovation and Research Building
Arlington, Texas, United States
Lipid profile (Total-C, LDL-C, VLDL-C, HDL-C, TG)
Time frame: Day 1
C-reactive protein
Time frame: Day 1
Post-occlusive brachial artery flow-mediated dilation (% change in brachial artery diameter from resting baseline)
Time frame: Day 1
Post-occlusive forearm reactive hyperemia (% change in brachial artery blood velocity from resting baseline)
Time frame: Day 1
Pulse wave velocity (carotid-to-femoral)
Time frame: Day 1
Augmentation index (AIx@HR75)
Time frame: Day 1
Cerebral vascular reactivity (% change in cerebrovascular conductance index from resting baseline)
Time frame: Day 2
Local cutaneous thermal hyperemia (% change in cutaneous vascular conductance from resting baseline)
Time frame: Day 2
Peripheral blood pressure (systolic, diastolic, mean)
Time frame: Day 1
Central blood pressure (systolic, diastolic, mean)
Time frame: Day 1
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