Relationship Between Serum N/OFQ and Brain-heart Syndrome

Zheng Guo120 enrolled

Overview

Choosing the neurology patients in the Second Hospital of Shanxi Medical University, diagnosed with patients with cerebral syndrome into the experimental group; patients who did not have cerebral syndrome included in the control group, and all selected people had no intimate relationship with each other.Specimen collecting control group and the study group serum inflammatory factor IL-6, solvent peptide and catecholamine content. The difference between the two groups of data was observed.According to the literature, it is guess: The solitary peptide content of the experimental group will be higher than the control group, and is positively correlated with IL-6, catecholamine content.The difference was statistically significant.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Cerebral-Cardiac Syndrome

Interventions

Enzyme-linked immunosorbent assayDIAGNOSTIC_TEST

Serum N/OFQ , IL-6 and NE levels were detected.

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnostic criteria in compliance with cerebral syndrome * Acute ischemic stroke patients in line with the "Chinese Acute Ischemic Stroke Treatment Guide 2018" related diagnostic criteria * There is no intimate relationship between all selected people and knows this study, and signs informed consent Exclusion Criteria: * Heart-type cerebral infarction, hemorrhagic stroke, brain tumor and past intracranial hemorrhage * Complicated with severe cardiovascular complications (such as coronary heart disease, acute coronary syndrome, acute myocardial infarction, chronic heart failure, atrial fibrillation, etc.) * Complicated with severe liver and kidney dysfunction (such as coagulous dysfunction, cirrhosis, nephrotic syndrome , Renal failure, etc.) * Complicated with severe diabetes complications (such as diabetic nephropathy, diabetic foot, diabetic acidosis, high blood sugar hypertonic state, diabetes coronary heart disease, etc.) * Complicated with Psychological disease * Complicated with chronic obstructive pulmonary disease(COPD) * BMI\> 40

Outcomes

Primary Outcomes

N/OFQ

Serum N/OFQ levels

Time frame: 24 hours

IL-6

Serum IL-6 levels

Time frame: 24 hours

Serum NE levels

Time frame: 24 hours

Relationship Between Serum N/OFQ and Brain-heart Syndrome

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes