Boswellia Serrata Extract in Acute Diarrhea

Azienda di Servizi alla Persona di Pavia49 enrolled

Overview

Acute diarrhea is a frequent problem worldwide, mostly due to gastrointestinal infections or food poisoning. Boswellia serrata could be active in the treatment of acute diarrhea due to its an-ti-inflammatory, antispasmodic and antimicrobial activity.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Acute Diarrhea Boswellia Serrata

Interventions

lecithin-based delivery form of Boswellia serrataDIETARY_SUPPLEMENT

250 mg for 5 days

PlaceboCOMBINATION_PRODUCT

250 mg for 5 days

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * presence of acute diarrhea of mild to moderate severity Exclusion Criteria: * patients with long term diarrhea * iatrogenic diarrhea * symptoms of functional gut disease or severe inter-current diseases * severe diarrhea and dehydration requiring hospitalization and intravenous treatment * subjects with high temperature (\> 38.5° C) * subjects treated by other anti-diarrheal and antibiotic drugs in the last 24 hours * severely malnourished subjects * pregnant women

Locations (1)

Azienda di Servizi alla Persona

Pavia, Italy

Outcomes

Primary Outcomes

Stoppage of diarrhea

the occurrence of the first formed stool or a period of 12 hours without any liquid or soft stools

Time frame: From baseline to 5 days

Secondary Outcomes

Self-assessed symptoms

daily number of stools within 5 days of treatment

Time frame: After 5 days

Self-assessed symptoms

percentage of subjects without diarrhea within 5 days of treatment

Time frame: After 5 days

Data from ClinicalTrials.gov

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