Recent evidence suggests that curcumin supplementation may reduce muscle inflammation, oxidative markers, and muscle damage. The most favourable dosage to elicit these ergogenic effects are yet to be established; both 750mg \& 1500mg has been shown to be effective. Curcumin supplementation has been ingested in numerous different ways however, no previous research to date has used curcumin in a hydrolysed (drinkable) format. The aim of this study is to investigate whether hydrolysed curcumin can reduce indices of muscle damage and improve recovery, whilst also examining a potential dose-response effect.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
36
Curcumin Supplementation
Blood markers
Blood samples will be taken for analysis of markers of IL-6, IL-1β, TNF-α, IL-1, IL-4, IL-10 and CK will be taken
Time frame: Baseline
Blood markers
Blood samples will be taken for analysis of markers of IL-6, IL-1β, TNF-α, IL-1, IL-4, IL-10 and CK will be taken
Time frame: immediately post muscle damage intervention
Blood markers
Blood samples will be taken for analysis of markers of IL-6, IL-1β, TNF-α, IL-1, IL-4, IL-10 and CK will be taken
Time frame: 24 hours post
Blood markers
Blood samples will be taken for analysis of markers of IL-6, IL-1β, TNF-α, IL-1, IL-4, IL-10 and CK will be taken
Time frame: 48 hours post
Blood markers
Blood samples will be taken for analysis of markers of IL-6, IL-1β, TNF-α, IL-1, IL-4, IL-10 and CK will be taken
Time frame: 72 hours post
Ford and Fort
Capillary sample Ford and Fort tests
Time frame: Baseline
Ford and Fort
Capillary sample Ford and Fort tests
Time frame: Immediately post muscle damage intervention
Ford and Fort
Capillary sample Ford and Fort tests
Time frame: 24 hours post
Ford and Fort
Capillary sample Ford and Fort tests
Time frame: 48 hours post
Ford and Fort
Capillary sample Ford and Fort tests
Time frame: 72 hours post
Soreness
Perceived muscle soreness scale - Visual analouge scale
Time frame: Baseline
Soreness
Perceived muscle soreness scale - Visual analouge scale
Time frame: Immediately post muscle damage intervention
Soreness
Perceived muscle soreness scale - Visual analouge scale
Time frame: 24 hours post
Soreness
Perceived muscle soreness scale - Visual analouge scale
Time frame: 48 hours post
Soreness
Perceived muscle soreness scale - Visual analouge scale
Time frame: 72 hours post
Soreness
BORG CR-10 scale
Time frame: Baseline
Soreness
BORG CR-10 scale
Time frame: Immediately post muscle damage intervention
Soreness
BORG CR-10 scale
Time frame: 24 hours post
Soreness
BORG CR-10 scale
Time frame: 48 hours post
Soreness
BORG CR-10 scale
Time frame: 72 hours post
Soreness
Pressure pain threshold
Time frame: Baseline
Soreness
Pressure pain threshold
Time frame: Immediately post muscle damage intervention
Soreness
Pressure pain threshold
Time frame: 24 hours post
Soreness
Pressure pain threshold
Time frame: 48 hours post
Soreness
Pressure pain threshold
Time frame: 72 hours post
Muscle Structure
Muscle swelling - thigh girth + Ultrasound measurement
Time frame: Baseline
Muscle Structure
Muscle swelling - thigh girth + Ultrasound measurement
Time frame: Immediately post muscle damage intervention
Muscle Structure
Muscle swelling - thigh girth + Ultrasound measurement
Time frame: 24 hours post
Muscle Structure
Muscle swelling - thigh girth + Ultrasound measurement
Time frame: 48 hours post
Muscle Structure
Muscle swelling - thigh girth + Ultrasound measurement
Time frame: 72 hours post
Muscle Function
maximal strength
Time frame: Baseline
Muscle Function
maximal strength
Time frame: Immediately post muscle damage intervention
Muscle Function
maximal strength
Time frame: 24 hours post
Muscle Function
maximal strength
Time frame: 48 hours post
Muscle Function
maximal strength
Time frame: 72 hours post
Muscle Function
Muscular endurance
Time frame: Baseline
Muscle Function
Muscular endurance
Time frame: Immediately post muscle damage intervention
Muscle Function
Muscular endurance
Time frame: 24 hours post
Muscle Function
Muscular endurance
Time frame: 48 hours post
Muscle Function
Muscular endurance
Time frame: 72 hours post
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