Dialectical Behavioral Therapy Skills for Impulsive Aggression

N/ACompletedNCT05351944

Alexandria University66 enrolled

Overview

This trial aims to Study the efficacy of DBT skills for impulsive aggression and executive dysfunctions in drug naïve children who are presented with impulsive aggression and ADHD and attending Child and adolescent clinic at Alexandria university hospitals using weekly group therapy for 8 month and testing pre and posttreatment biomarkers of aggression.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Impulsive Aggression ADHD Executive Dysfunction

Interventions

Dialectical behavioral therapy skills for the intervention experimental group ABEHAVIORAL

Our hypothesis is that impulsive aggression as evidenced by inflammatory biomarkers might improve by targeting executive dysfunctions with Dialectical Behavioural Therapy skills modules directed to the children and their parents in the form of response inhibition dysfunctions with Dialectical Behavioural Therapy mindfulness and distress tolerance skills modules, emotion regulation executive dysfunctions with Dialectical Behavioural Therapy emotion regulation skills module and socioenvironmental factors with interpersonal effectiveness and walking the middle path Dialectical behavioural therapy skills modules.

psychoeducation or Atomoxetine or stimulants according to ADHD severityDRUG

the control group (group B) will receive psychoeducation and medications targeting ADHD symptoms (Atomoxetine or stimulants according to FDA approved dose according to age and weight ) according to the international guidelines for management of ADHD according to symptom severity

Eligibility

Sex: MALEMin age: 6 YearsMax age: 13 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients from 6 to 13-year-old. * Patients diagnosed with ADHD and presented with impulsive aggression. * Commitment to therapy from the child and the parent. * Written consent of all the children parents. * Male gender. * Drug naïve or stopped medications for at least one month. Exclusion Criteria: * Patients younger than 6 years of age as it's the starting age for DBT-C. * Patients who dropped from DBT skills group (missing more than 3 consecutive sessions) whether the child or his parent. * Patients diagnosed with drug abuse. * Patients with severe sensory impairment or intellectual disability. * Drug induced aggression as levetiracetam, topiramate and benzodiazepines. * Patients diagnosed with Autism spectrum disorder or psychotic disorders.

Locations (1)

Alexandria university

Alexandria, Egypt

Outcomes

Primary Outcomes

Impulsive aggression severity

Using Modified overt aggression scale ,This scale rates the patient's aggressive behavior regarding four types of aggression (verbal, against objects, against self, against others) to give a total MOAS score about the patient's aggressive behavior. Each type of aggression had a rating of 0 when aggression was absent and four levels of severity. Weighted scores are then added together to yield the total score.

Time frame: Change from Baseline at 12 month

Biomarkers of aggression 1

quantitative CRP