Lung Scintigraphy for Pulmonary Embolism Diagnosis in COVID-19 Patients.

University Hospital, Brest183 enrolled

Overview

A frequent complication of COVID-19 disease is pulmonary embolism (PE). Lung ventilation/perfusion (V/P) scintigraphy is a well-established test for PE diagnosis. The test is interpreted based on the recognition of wedge shaped perfusion mismatched defects. However, the ventilation procedure increases the potential risk of contamination by the aerosol secretion and the expired air. A variety of strategies have been proposed in the nuclear medicine literature regarding performance of lung ventilation scintigraphy in COVID-19 patients with suspected acute PE. However, there is currently no factual data in this specific population to support recommendations to the nuclear medicine community. The aim of this study was to assess the role of ventilation imaging when performing lung scintigraphy for suspected PE in COVID-19 patients.

Study Type

OBSERVATIONAL

Enrollment

183

Conditions

Pulmonary Embolism COVID-19

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with suspected COVID-19 disease * Referred for lung scintigraphy for suspected acute PE Exclusion Criteria: * Patient under guardianship or curatorship * Patient deprived of liberty by an administrative or judicial decision * Inability or refuse to give consent

Locations (2)

Outcomes

Primary Outcomes

PE diagnosis on lung scintigraphy without the ventilation scan.

Percentage of scans for which the diagnostic conclusion of the lung scan would have been different when omitting the ventilation scan

Time frame: 1 day