Perioperative Respiratory Adverse events_sugammadex

Seoul National University Hospital174 enrolled

Overview

Perioperative respiratory adverse events are common in children. We aimed to evaluate the effect of sugammadex on the incidence of perioperative respiratory adverse events in pediatric patients receiving tonsillectomy

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

QUADRUPLE

Enrollment

174

Conditions

Respiratory Complication

Interventions

Sugammadex injectionDRUG

sugammadex as reversal agent

NeostigmineDRUG

neostigmine as a reversal agent

Eligibility

Sex: ALLMin age: 2 YearsMax age: 6 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Pediatric patients aged 2-6 years who were scheduled for tonsillectomy under general anesthesia were enrolled Exclusion Criteria: * a recent history of upper respiratory tract infection within 2 weeks of surgery * allergic reaction to sugammadex * renal failure * liver failure * arrhythmia

Locations (1)

Seoul national university hospital

Seoul, South Korea

Outcomes

Primary Outcomes

Perioperative respiratory adverse events

the incidence of overall perioperative respiratory adverse events; oxygen desaturation \< 95%, airway obstruction, laryngospasm, bronchospasm, severe coughing, or postoperative stridor