The purpose of this research study is to assess if autologous Stromal Vascular Fraction (SVF) taken from the stomach or hips can help heal vocal fold scars.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
2
A single dose of autologous adipose derived SVF isolated from adipose tissue will be administered to scarred vocal folds.
Mayo Clinic Florida
Jacksonville, Florida, United States
Adverse events post SVF administration
Number of adverse events related to SVF via endoscopy into vocal folds defined as inflammation or swelling indicated by red or swollen vocal folds or evidence of a hemorrhage indicated by a bleed at or near the site of delivery. This will be evaluated during stroboscope exam.
Time frame: 24 months
Voice handicap Index
Change in the self-reported voice handicap index to describe voices and effects of voices on subject lives, measure using a total score range from 0-120; 0-30=mild, 31-60=moderate, 60-120=severe
Time frame: Baseline, Week 1, and Months 1, 3, 6, 9, 12, and 24
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