Effects of Combinations of Performance-enhancing Supplements on Exercise Performance

Morten Hostrup, PhD23 enrolled

Overview

The purpose of the study is to investigate the effect of combinations of creatine monohydrate, sodium bicarbonate and caffeine on exercise performance and fatigability.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

QUADRUPLE

Enrollment

Conditions

Healthy

Interventions

Sodium bicarbonate and caffeineDIETARY_SUPPLEMENT

On experimental days subjects ingest a combination of sodium bicarbonate, caffeine and placebo.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy * VO2max of \>50 ml/min/kg for men and \>45 ml/min/kg for women * Performs endurance training \>3 times per week Exclusion Criteria: * Chronic disease deemed by the study responsible medical doctor to interfere with any part of the study * Smoking * Chronic use of prescription medicine deemed by the study responsible medical doctor to interfere with any part of the study

Locations (1)

August Krogh Building

Copenhagen, Denmark

Outcomes

Primary Outcomes

Work performed (kJ/Watt)

Work performed during a 6 minute time trial

Time frame: Measured at each trial throughout the study, on average 4 weeks

Secondary Outcomes

Work performed (kJ/Watt)

Work performed during a 15 second sprint test

Time frame: Measured at each trial throughout the study, on average 4 weeks

Muscle strength (Nm)

Maximal voluntary isometric contraction of m. quadriceps femoris

Time frame: Measured at each trial throughout the study, on average 4 weeks

Data from ClinicalTrials.gov

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