This study aims to determine the feasibility and preliminary data on the interaction between oxytocin and cortisol during stress in borderline personnality disorder.
The investigators will recruit 50 female patients with borderline personnality disorder and 50 controls with no psychiatric diagnosis, aged between 18 and 25 years old. salivary cortisol daily curve ( 6 measures during the day) will be measured in participant's naturalistic environnement, together with salivary oxytocin. In addition, salivary oxytocin and cortisol will be measured during a psychosocial stress task and recovery.
Study Type
OBSERVATIONAL
Enrollment
100
TSST- psychosocial stress test
Young Adult Psychiatric Unit
Geneva, Canton of Geneva, Switzerland
Salivary cortisol
salivary cortisol measured with salivettes (swabs)
Time frame: Baseline
Salivary cortisol
salivary cortisol measured with salivettes (swabs)
Time frame: Change in one day (circadian cortisol with 6 measures within one day
Salivary cortisol
salivary cortisol measured with salivettes (swabs)
Time frame: Change during experimental task (up to 2 hours)
Salivary oxytocin
salivary oxytocin measured with salivettes (swabs)
Time frame: Baseline
Salivary oxytocin
salivary oxytocin measured with salivettes (swabs)
Time frame: Two measures within one day
Salivary oxytocin
salivary oxytocin measured with salivettes (swabs)
Time frame: Change during experimental task (up to 2 hours)
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