Study of Neutrophils and Circulating Platelets in Correlation With the Activity of T Lymphocytes in Patients With NAFLD (Nonalcoholic Fatty Liver Disease)

University of L'Aquila80 enrolled

Overview

The aim of the study is to define the relationship between neutrophils, platelets and the activity of T lymphocytes in patients with NAFLD (nonalcoholic fatty liver disease). This study may predict, in the course of hepatic steatosis, specific phenotypic patterns expressed by PMNs and circulating platelets to evaluate their role in disease progression.

Study Type

OBSERVATIONAL

Enrollment

Conditions

NAFLD- Non Alcoholic Fatty Liver Disease

Interventions

Data collectionDIAGNOSTIC_TEST

Clinical data collection

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients over 18 * No alcoholic abuse * Hepatic steatosis diagnosticated by abdominal ultrasound * Negative hepatitis B and C tests * No history of hepatic cirrhosis Exclusion Criteria: * Under 18 * History of alcoholic abuse * Positive serology for hepatitis B or C * History of hepatic cirrhosis

Locations (1)

Clara Balsano

L’Aquila, Italy/L'Aquila, Italy

RECRUITING

Outcomes

Primary Outcomes

IL-8(interleukin 8)

Time frame: 12 months

Morphology of Circulating Platelets in healthy donors, NAFL, and NASH patients wondering how they may drive and modulate the activity of T cells in this disease

Time frame: 12 months

Platelets count in healthy donors, NAFL, and NASH patients

Time frame: 12 months

number of Neutrophilis

Time frame: 12 months

Morphology of Neutrophilis

Time frame: 12 months

Data from ClinicalTrials.gov

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