Stroke Volume Variation-guided Fluid Infusion in Major Liver Tumour Resection

Kaohsiung Veterans General Hospital.118 enrolled

Overview

Studies have demonstrated that the rate of change in stroke volume variation (SVV) can be used to determine the volume of body fluids during major abdominal surgery. Anaesthesiologists can use SVV as a guide for the appropriate administration of intraoperative fluids to improve postoperative prognoses. Liver surgery is a major abdominal operation, and the amount of blood lost is typically higher than that during other general abdominal surgeries. Blood loss is positively correlated with the intraoperative fluid infusion volume, and greater blood loss is associated with more postoperative complications. Additionally, comorbid liver disease or cirrhosis can increase the complexity of liver tumour resection, causing difficulty in assessing intravascular volume and determining the appropriate intraoperative infusion volume.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

118

Conditions

Fluid Management

Interventions

Eligibility

Sex: ALLMin age: 20 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * We initially selected 118 patients who required hepatectomy. * The physiological status of the patients was assessed in terms of American Society of Anesthesiologists scores I-III Exclusion Criteria: * Extreme body mass index (BMI) * Age under 20 or over 75 years * Emergency surgery * Preexisting cardiac, hepatic, renal, or coagulation disorder; hyperthyroidism; and sinus arrhythmia.

Outcomes

Primary Outcomes

The incidence of postoperative complications in the two groups.

calculate the incidence of postoperative complication within 30 days

Time frame: From day 1 to day 30 after surgery.