Prenatal Diagnosis of the Fetal Esophageal or Intestinal Atresia

Poitiers University Hospital51 enrolled

Overview

Aim- to investigate how prenatal diagnosis of fetal esophageal or intestinal atresia impacts obstetric and neonatal outcomes. Methods- This was a retrospective cohort study at a single center. The study population comprised 51 consecutive pregnancies, including 29 mothers (57%) and their fetuses affected by prenatally diagnosed fetal esophageal or intestinal atresia, and 22 mothers (43%) and their babies with postnatally diagnosed fetal esophageal or intestinal atresia.

Aim- to investigate how prenatal diagnosis of fetal esophageal or intestinal atresia impacts obstetric and neonatal outcomes. Methods- This was a retrospective cohort study at a single center. The study population comprised 51 consecutive participants, including 29 mothers (57%) and their fetuses affected by prenatally diagnosed fetal esophageal or intestinal atresia, and 22 mothers (43%) and their babies with postnatally diagnosed fetal esophageal or intestinal atresia.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Antenatal Management of the Fetal Gastrointestinal Atresia

Interventions

scheduled delivery at a tertiary centerPROCEDURE

Neonatal units in French hospitals are classified in three levels. The intention is for infants requiring high level care to receive it in a tertiary neonatal unit within the same network when appropriate. In case of known fetal gastro-intestinal artesia, the prenatal care includes obstetric consultation and level 3 ultrasound scheduled every four weeks at our unit until the end of the pregnancy, antenatal consultations with a specialized multidisciplinary team, and an antenatal visit of the birth center to reduce the parental anxiety.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * all pregnancies affected by fetal esophageal, duodenal or intestinal atresia referred to our prenatal diagnosis unit * all newborns managed for such atresia in our unit of pediatric surgery Exclusion Criteria: * termination of pregnancy, * stillbirth, * the false positive cases

Locations (1)

Centre Hospitalier Universitaire de Poitiers

Poitiers, France

Outcomes

Primary Outcomes

gestational age of delivery

weeks

Time frame: 1 year

mode of delivery

Vaginal, Operative vaginal, Elective cesarean section, Cesarean section for fetal indication

Time frame: 1 year

Secondary Outcomes

neonatal morbidity

Age at surgery, Cutaneous stoma, Anastomotic leakage, Mechanical ventilation, Phototherapy, Infection

Time frame: 1 year

length of hospital stay

Length of neonatal intensive care unit stay, Length of neonatal reanimation stay (days)

Time frame: 1 year

Data from ClinicalTrials.gov

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