RISE FOR HEALTH Study

University of Minnesota3,400 enrolled

Overview

The RISE FOR HEALTH study (RISE) is an initiative of the Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium, which was formed by the NIDDK in 2015 to develop the science to improve bladder health in women and girls. RISE is designed to identify risk and protective factors for bladder health and lower urinary tract symptoms (LUTS) and to estimate the distributions of bladder health and bladder health knowledge, attitudes, and beliefs in women of all ages across the life course. This will be accomplished by conducting a population-based prospective cohort study. A sample of individuals who live within the study base, i.e., the county containing each PLUS clinical research center and each adjacent county, will be invited to complete two baseline surveys and then two follow-up surveys one year later. A subset of participants will be invited to attend an in-person evaluation to collect additional clinical information and biologic specimens.

Study Type

OBSERVATIONAL

Enrollment

3,400

Conditions

Lower Urinary Tract Symptoms

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Community dwelling * Age ≥18 years * Identify or born as female (includes cis- and trans-women, and trans-men) * Able to read and understand English or Spanish * Able to read and provide informed consent Exclusion Criteria: * Physical or mental health conditions that would prohibit self-administration of questionnaires either electronically or using paper and pencil (e.g., dementia/cognitive impairment/blindness/severe arthritis). * Residence in a nursing home or other institutionalized living facility.

University of Alabama at Birmingham

Birmingham, Alabama, United States

University of California, San Diego

San Diego, California, United States

Yale University

New Haven, Connecticut, United States

Emory University

Atlanta, Georgia, United States

Loyola University Chicago

Chicago, Illinois, United States

Northwestern University

Chicago, Illinois, United States

University of Michigan

Ann Arbor, Michigan, United States

Washington University School of Medicine

St Louis, Missouri, United States

University of Pennsylvania

Philadelphia, Pennsylvania, United States

Outcomes

Primary Outcomes

Bladder Health Scales and Function Indices

Multi-item measurement to assess bladder health comprised of subscales and indices ranging from zero to 100

Time frame: Baseline assessment

Secondary Outcomes

Knowledge, Attitudes and Beliefs (KAB)

Several questions on knowledge, attitudes, and beliefs regarding bladder health and influences on bladder health

Time frame: Baseline assessment

Change in Bladder Health Scales and Function Indices

Change in multi-item measurement to assess bladder health comprised of subscales and indices ranging from zero to 100

Time frame: 1 year follow-up from baseline assessment