In this prospective multi-center randomized clinical trial, a new follow-up strategy for neonatal jaundice after discharge will be evaluated. It is based on current risk factors of neonatal hyperbilirubinemia, added with the rate of bilirubin production (exhaled carbon monoxide measurement) as a new indicator,and incorporated with Internet Plus technology. Traditional methods following the Chinese guideline for neonatal hyperbilirubinemia were applied in the control group. The morbidity of BIND, the number of outpatient follow-up after discharge and the convenience will be compared between the two groups. The accuracy, effectiveness, safety and convenience of the study strategy will be testified.
The eligible newborns will be randomized into two groups: the study group (innovative strategy) and the controlled group (traditional strategy). The innovative strategy included the ETCOc measurement in the risk evaluating process and the Internet Plus approach in the follow-up process.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
2,500
The measurement of end tidal carbon monoxide corrected for ambient carbon monoxide (ETCOc)is conducted in the process of risk evaluation.
The Internet Plus technology is applied in the process of follow-up management.
the incidence of acute bilirubin encephalitis
the number of infants with acute bilirubin encephalitis in each group
Time frame: within 2 week after birth
the bilirubin level of readministration for hyperbilirubinemia
the average bilirubin level of infants, who are readmitted for hyperbilirubinemia
Time frame: within 1 months
the cost for the issue of jaundice follow-up
compare the fee for intelligent follow-up with the fee for clinical visiting according to present jaundice follow-up suggestion
Time frame: within 1 month
the time for the issue of jaundice follow-up
compare the time for intelligent follow-up,including the time for TSB measurement and internet commuication,with the time for clinical visiting according to present jaundice follow-up suggestion
Time frame: within 1 month
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