This study aims to examine 1) if multicomponent exercise interventions (including both mobility and strengthening exercises) have effects on physical function compared to usual care in older adults, and 2) if a comprehensive multicomponent exercise program is more effective than a simple multicomponent exercise program including only walking and rising from a chair.
This is a three-armed randomized controlled trial, with two intervention groups (comprehensive and simple exercise program) and a control group receiving usual care. Participants aged ≥75 years will be included consecutively from geriatric medical wards of hospitals in Stockholm, Sweden. Assessments will be conducted at hospital admission, discharge and three months thereafter concerning physical function (primary outcome), activities of daily living, health-related quality of life, sarcopenia, and falls. Number of re-admissions and mortality will be registered up to 1 year after discharge.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
320
Up to four sessions per day (total duration 20-30 minutes/day). Performed at the hospital on all weekdays from baseline until hospital discharge (around 1 week). At discharge, the participants will be encouraged to continue with the exercise program at home.
Two daily sessions (morning and afternoon) of 20 minutes' duration each. Performed at the hospital on all weekdays from baseline until hospital discharge (around 1 week).
Anna-Karin Welmer
Huddinge, Sweden
RECRUITINGPhysical function
Short Physical Performance Battery (Possible score: 0-12), a higher score represents a better physical function)
Time frame: Change from baseline (hospital admission) to completion of the hospital-based exercises (at discharge around 1 week after baseline)
Physical function
Short Physical Performance Battery (Possible score: 0-12), a higher score represents a better physical function)
Time frame: Change from baseline (hospital admission) to 3 months after discharge
Activities of daily living
Barthel Index (Possible score: 0-100, a higher score represents a better functional ability)
Time frame: Change from baseline (hospital admission) to completion of the hospital-based exercises (at discharge around 1 week after baseline)
Activities of daily living
Barthel Index (Possible score: 0-100, a higher score represents a better functional ability)
Time frame: Change from baseline (hospital admission) to 3 months after discharge
Health related quality of life
EuroQol-5 Dimension
Time frame: Change from baseline (hospital admission) to completion of the hospital-based exercises (at discharge around 1 week after baseline)
Health related quality of life
EuroQol-5 Dimension
Time frame: Change from baseline (hospital admission) to 3 months after discharge
Sarcopenia
Defined by grip strength and calf- and arm circumferences according to the European Working Group's revised criteria on Sarcopenia in Older People
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Time frame: Change from baseline (hospital admission) to completion of the hospital-based exercises (at discharge around 1 week after baseline)
Sarcopenia
Defined by grip strength and calf- and arm circumferences according to the European Working Group's revised criteria on Sarcopenia in Older People
Time frame: Change from baseline (hospital admission) to 3 months after discharge
Number of falls
According to the logbooks at the hospital
Time frame: Change from baseline (hospital admission) to completion of the hospital-based exercises (at discharge around 1 week after baseline)
Number of falls
According to self-report
Time frame: From hospital discharge to 3 months after discharge
Mortality data
Data on vital status will be collected using administrative data
Time frame: Up to 1 year after hospital discharge
Number of readmissions
Data on readmissions will be collected using administrative data
Time frame: Up to 1 year after hospital discharge