* Assess predictors of mortality in COPD exacerbation between men and women. * Evaluate the clinical outcomes in acute exacerbation of COPD in women. * Evaluate the validity of new scoring systems ( NIVO, DECAF, HACOR ) as a predictor for hospital outcome in acute exacerbation of COPD. * Compare these new scoring system with the most widely used APACHE IV. * Assessment of serum level of granulocyte colony stimulating factor ( GM-CSF) in detecting the severity of COPD exacerbation.
Study Type
OBSERVATIONAL
Enrollment
203
Mortality rate among COPD patients hospitalized due to acute exacerbation.
Assessment of mortality with different scoring systems in acute exacerbation of COPD
Time frame: 28 days from admissiom
Early prediction of NIV failure.
Using NIVO score for Acute exacerbaion of COPD Non-invasive ventilation outcomes score is considered to be Low risk ( 0-2) Moderate risk (3-4) High risk (5-6) Very high risk ( 7-9)
Time frame: 48 hours from ICU admission
Assessment of GM-CSF as a biomarker for successful therapy in acute exacerbation of COPD.
Assessment of granulocyte colony stimulating factor by ELISA test in acute exacerbation of COPD
Time frame: baseline
Assisted ventilation days.
Estimating the number of days required for either non-invasive or invasive mechanical ventilation
Time frame: Baseline
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