Multiple Ascending Dose Study of CM338 in Healthy Volunteers

Inclusion Criteria: * Healthy male volunteers, aged ≥18 and ≤65 years. * Medical history, vital signs, physical examination, 12-lead ECG, X-ray, and abdominal color ultrasound results are normal, or abnormal without clinically significance. * All clinical laboratory examination are normal, or abnormal without clinical significance. Exclusion Criteria: * Take any prescription medicine within 2 weeks before administration, or take any Chinese medicine or non-prescription medicine within 1 week. * Live attenuated vaccine was administered within 30 days prior to administration or planned to vaccinate during the study period. * Major surgery will be planned during the study period, or major surgery was performed within 4 weeks prior to dosing. * Any blood loss greater than 400 mL by voluntary blood donation or in any other manner within 4 weeks prior to administration.