Collecting Ducts Carcinoma: in Depth Exploration and Biologically Driven Therapy (CICERONE)

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano100 enrolled

Overview

* Collect a large number of samples with certain / suspected diagnosis of collecting duct carcinoma in order to confirm the diagnosis (centralized review) and standardize according to WHO 2016 criteria * Build an extensive tissue bank (DNA and RNA extraction) aimed at defining the molecular taxonomy of the tumor through 1) transcriptomic analysis 2) gene expression profile * Define specific molecular signatures

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Collecting Duct Carcinoma

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 18 years * Signature of consent (for patients enrolled in the prospective part of the study) * Histological diagnosis of renal cell carcinoma of the Bellini collecting duct RCC Exclusion Criteria: \-

Locations (1)

Fondazione IRCCS Istituto Nazionale Tumori

Milan, Italy

RECRUITING

Outcomes

Primary Outcomes

samples to confirm and standardize

Collect a large number of samples with certain / suspected diagnosis of collecting duct carcinoma in order to confirm the diagnosis (centralized review) and standardize it according to WHO 2016 criteria

Time frame: 15 month

Secondary Outcomes

Tissue Bank

Build an extensive tissue bank (DNA and RNA extraction) aimed at defining the molecular taxonomy of the tumor through 1) transcriptomic analysis 2) gene expression profile

Time frame: 15 month

specific molecular signatures

Define specific molecular signatures

Time frame: 15 month

Central Contacts

Elena Verzoni, MD

CONTACT

0223904449 elena.verzoni@istitutotumori.mi.it

Roberta Mennitto, Dr.ssa

CONTACT

0223903884 roberta.mennitto@istitutotumori.mi.it

Data from ClinicalTrials.gov

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