Infertility is a disease that seriously affects the physical and mental health of women of childbearing age. The incidence of infertility has been increasing in recent years. Studies have shown that the occurrence of infertility may be related to environmental endocrine disrupting substances. This project was designed to establish a cohort study on environmental endocrine disrupting substances and in vitro fertilization (IVF) treatment, collect blood, urine, semen, follicular fluid, granulosa cells, chorionic decidua biological specimens, and then follow up on the pregnancy outcomes. The concentration of disrupting substances was detected and then found the associations between environmental endocrine disrupting substances and female reproductive health.
Study Type
OBSERVATIONAL
Enrollment
2,000
there is no intervention in the study
Peking University People's Hospital
Beijing, Beijing Municipality, China
RECRUITINGNumber of eggs retrieved
the number of eggs retrieved in the process of in vitro fertilization (IVF)
Time frame: immediately after the eggs retrieved
the number of available embryos
the number of available embryos in the process of IVF
Time frame: 1 week after the eggs retrieved
the clinical pregnancy rate
the clinical pregnancy rate in the process of IVF
Time frame: 4 weeks after the embryos transfer
the miscarriage rate
the miscarriage rate in the process of IVF
Time frame: 7 months after embryos transfer
the live birth rate
the live birth rate in the process of IVF
Time frame: 40 weeks after embryos transfer
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