LARS for Chinese Patients

Third Affiliated Hospital, Sun Yat-Sen University261 enrolled

Overview

Low anterior resection syndrome (LARS) frequently occurs in patients undergoing low anterior resection (LAR). However, the incidence, exact mechanism and risk factors of major LARS largely variate in different studies. Considering varieties and differences of patient characteristics between Chinese patients and the western ones, this retrospective study aims to investigate the incidence of LARS in Chinese patients undergoing laparoscopic LAR, and to explore perioperative risk factors that might be associated with major LARS. Consequent patients undergoing laparoscopic LAR and free from disease recurrence from January 2015 to May 2021 were issued with LARS questionnaire. Incidence of LARS and patient data were collected and analyzed.

Study Type

OBSERVATIONAL

Enrollment

261

Conditions

Incidence and Risk Factors of Low Anterior Resection Syndrome

Interventions

LARS questionnaireDIAGNOSTIC_TEST

Eligible participants were issued with LARS questionnaire (Chinese version) by E-mail, message, phone or face to face interview.

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Patients diagnosed as rectal cancer and underwent radical laparoscopic LAR and straight colorectal/coloanal anastomosis (with or without a protective stoma) by a same surgical team Exclusion Criteria: either local or distal recurrence, severe complications such as postoperative anastomotic leakage, failure of protective stoma closure, data missed and no responding to LARS questionnaire

Outcomes

Primary Outcomes

incidence of LARS

incidence of Low Anterior Resection Syndrome

Time frame: at least 1 months postoperatively

incidence of major LARS

incidence of major Low Anterior Resection Syndrome