Long lasting inflammation in the body is related to cardiovascular and respiratory disease, which are the two most common causes of death in people living with spinal cord injury (SCI). Individuals with SCI have been reported to have higher levels of inflammation when compared to healthy individuals. Exercise is a well-known method to reduce inflammation; however, people with SCI are often inactive. The main goal of this study is to determine whether a 12-week adaptive exercise program can reduce inflammation in people with SCI. Participants will be randomized to start exercise immediately or after a 12-week delay.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
A 12-week exercise program geared towards individuals with neurological disorders or injuries run by the Regions Hospital Rehabilitation department at the HealthPartners Neuroscience Center. The exercise programming will be designed by the exercise physiologists and adapted to individuals' abilities. Exercise prescriptions will be designed based on established guidelines, level and completeness of injury, individual functional ability, individual goals, and baseline exercise assessments. Program will consist of strength and endurance adaptive exercise.
HealthPartners Neuroscience Center
Saint Paul, Minnesota, United States
Effect of Exercise on Inflammation (C-reactive Protein)
Change in C-reactive protein after 12 week exercise program
Time frame: 12 weeks
Effect of Exercise on Inflammation (Interleukin 6)
Change in Interleukin 6 after 12 week exercise program
Time frame: 12 weeks
Effect of Exercise on Inflammation (Tumor Necrosis)
Change in Tumor Necrosis Biomarker after 12 week exercise program
Time frame: 12 weeks
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