The objective of this study is to evaluate the pharmacokinetics and safety of cedirogant following oral administration of multiple doses in adult participants with hepatic impairment and normal hepatic function.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
6
Capsule, Oral
Clinical Pharmacology of Miami /ID# 246573
Miami, Florida, United States
Orlando Clinical Research Ctr /ID# 246052
Orlando, Florida, United States
TX Liver Inst, Americ Res Corp /ID# 246572
San Antonio, Texas, United States
Maximum Observed Plasma Concentration (Cmax)
Maximum Observed Plasma Concentration
Time frame: Up to 18 Days
Time to maximum observed plasma concentration (Tmax)
Time to maximum observed plasma concentration
Time frame: Up to 18 Days
Area under the plasma concentration-time curve (AUC) from time 0 to 24 hours after dosing (AUC0-24)
AUC from time 0 to 24 hours after dosing
Time frame: Up to 18 Days
Number of Participants with Adverse Events
An adverse event (AE) is defined as any untoward medical occurrence in a participant or clinical investigation participant administered a pharmaceutical product which does not necessarily have a causal relationship with the treatment. The investigator assesses the relationship of each event to the use of study drug.
Time frame: Up to 44 Days
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