This study is being conducted to determine the relationship between early childhood exposures, such as Adverse Childhood Experiences, Social Determinants of Health and nutrition/breastfeeding, among children with sickle cell disease, and behavioral interventions aimed to reshape psychological resilience and lifestyle factors towards positive health outcomes.
During year 3 of the award period, 20 mother-infant dyads will be randomly assigned to either a community-based breastfeeding support group or observation. Acceptability to enrollment, intervention adherence for at least 6 months and preliminary effectiveness will be captured. Biomarkers of inflammation, development of asthma and incidences of pain and/or acute chest syndrome will be compared among the intervention and control groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
20
community-based breastfeeding support group aimed to increase exclusive breastfeeding success rates among Black women
Observe prospectively for breastfeeding initiation, duration and longitudinal health of child with sickle cell disease
University of Alabama at Birmingham
Birmingham, Alabama, United States
RECRUITINGAcceptance and Retention of Mothers of Infants with Sickle Cell Disease to a Community-based Breastfeeding Intervention
acceptance (number of mothers enrolled/number of mothers approached) and retention (number of mothers to complete 6 month support group intervention/number enrolled)
Time frame: 6 months
Preliminary Effectiveness
Percentage of mothers of infants with sickle cell disease that successful complete 6 months of breastfeeding, comparing the intervention vs. control groups
Time frame: 2 years
Asthma
Prevalence of asthma among children with sickle cell disease that were breastfed compared to those that were not
Time frame: 4 year follow up period
Acute chest syndrome
Incidence rate of episodes of acute chest syndrome among children with sickle cell disease that were vs. were not breastfed
Time frame: 4 year follow up period
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