Functional dyspepsia (FD) is a common gastrointestinal disease with high morbidity. Due to the drop in estrogen level, perimenopausal women with FD (PMFD) have an increase in emotional disorders such as depression, anxiety and sleep disorder.
the research will include 30 FD women during their perimenopause to receive for 8 weeks the following: relaxation therapy (Benson relaxation), physical exercise (on treadmill), and proton pump inhibitors. Also, the research will include another 30 FD women during their perimenopause to receive for 8 weeks the following: relaxation therapy (Benson relaxation) and proton pump inhibitors
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
60
This FD women group will include 30 females who will be treated for 8 weeks with oral proton pump inhibitors (taken one time daily with 40 mg pantoprazole-tablet dose), Benson relaxation daily sessions (twenty minutes at morning time and another 20 minutes at the evening time), physical activity ( five session per the week conducted on treadmill, 30 minutes in the first treatment month and 40 minutes in the second treatment month)
This FD women group will include 30 females who will be treated for 8 weeks with oral proton pump inhibitors (taken one time daily with 40 mg pantoprazole-tablet dose) and Benson relaxation daily sessions (twenty minutes at morning time and another 20 minutes at the evening time)
Faculty of Physical Therapy Cairo University
Giza, Dokki, Egypt
RECRUITINGcortisol
stress hormone will be measured in serum
Time frame: It will be measured after 8 weeks
Glasgow dyspepsia severity score
it is questionnaire assessing severity of dyspepsia
Time frame: It will be measured after 8 weeks
Visual analogue scale
it is a scale for assessment of severity of abdominal syymptoms
Time frame: It will be measured after 8 weeks
depression anxiety stress scales-42
it is a 42 item self-report scale designed to measure the negative emotional states of depression, anxiety and stress
Time frame: It will be measured after 8 weeks
Pittsburgh sleep quality index
it is a questionnaire for sleep quality assessment
Time frame: It will be measured after 8 weeks
Estradiol
one of endogenous estrogen in the serum of women
Time frame: It will be measured after 8 weeks
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