A Cross-sectional Study of Lipoprotein(a) Levels in Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD)

Amgen39,480 enrolled

Overview

The purpose of this study is to characterize the distribution of lipoprotein(a) (Lp(a)) levels among participants with a history of ASCVD as defined by their medical history and is 2-fold: * Evaluate the distribution of Lp(a) value in the overall participants with documented history of ASCVD * Evaluate the distribution of Lp(a) value in participants with documented history of ASCVD by demographics and regions

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

39,480

Conditions

Atherosclerotic Cardiovascular Disease

Interventions

Lp(a) ScreeningOTHER

Participants will provide demographic information and have a blood draw for Lp(a) levels if they are unknown.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Signed informed consent * History of ASCVD Exclusion Criteria: * Participants known to be currently receiving investigational drug in a clinical study * Participants with a diagnosis of end-stage renal disease or requiring dialysis * Participants who have received lipoprotein apheresis to reduce Lp(a) within 3 months prior to enrollment

Locations (735)

Outcomes

Primary Outcomes

Number of participants with elevated Lp(a) with documented history of ASCVD

Time frame: Up to approximately 2 weeks

Secondary Outcomes

Lp(a) Levels

Blood sampling will be performed in cases where Lp(a) values are not available at enrollment. In cases where Lp(a) values are available, data will be collected retrospectively.

Time frame: Up to approximately 2 weeks

Lp(a) Levels stratified by demographics and region

Time frame: Up to approximately 2 weeks

Data from ClinicalTrials.gov

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