In critical ill patients, feeding protocol is one of the important factor which determines the successful implementation of enteral nutrition(EN). Acute gastrointestinal injury(AGI) affects feeding tolerance, which greatly determines the successful implementation of feeding protocol. In our previously study, we found that transabdominal intestinal sonography is helpful to diagnosis AGI. Thus in this study ,we apply transabdominal gastrointestinal sonography to feeding protocol, to assess the feasibility of gastrointestinal sonography assisted enteral nutrition and its impact on critical ill patients.
Patients meeting inclusion and exclusion criteria were randomly assigned to the intervention group and control group. During the first week of initiation of nutrition, enteral nutrition was conducted according to different procedures to observe the impact of different feeding procedures on clinical indicators
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
294
Once the critical ill patients is stable, enteral nutrition was initiated following a procedure assisted by gastrointestinal ultrasound.
Nanjing Drum Tower Hospital
Nanjing, Jiangsu, China
Target-reaching rate through enteral route
percentage of participants who reach target calorie through enteral route
Time frame: Within first week
The incidence of feeding intolerance
Time frame: Within first week
The application of parenteral nutrition
Time frame: Within first week
The application of prokinetic drugs
Time frame: Within first week
The ues of vasoactive drugs
Time frame: Within first week
Mechanical ventilation
Time frame: Within first week
Continuous renal replacement
Time frame: Within first week
The CRP level
Time frame: Day0/1/3/5/7
Mortality
Time frame: Day28、Day60、during hospitalization
ICU length of stay
Time frame: During ICU stay
Length of hospital stay
Time frame: During hospital stay
Platelet count
Time frame: Day0,1,3,5,7
Total bilirubin
Time frame: Day0,1,3,5,7
Serum creatinine
Time frame: Day0,1,3,5,7
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