This study examines how people respond to rewards and losses, and the extent to which these responses are linked or distinct among people experiencing depressed mood, anhedonia, and/or anxiety.
This study tests relationships among neural and behavioral valuation mechanisms, and how these mechanisms change (or not) over time, with task instructions, and following cognitive behavior therapy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
252
cognitive behavioral therapy
repeat laboratory sessions of computerized learning game
repeat laboratory sessions of computerized learning game
Fralin Biomedical Research Institute at Virginia Tech Carilion
Roanoke, Virginia, United States
RECRUITINGchange in proportion correct on the 'N-arm bandit learning task'
change in proportion correct on 'N-arm bandit reinforcement learning task' from study entrance to study exit
Time frame: study entrance to study exit, an average of 12 weeks
change in depression symptoms (Beck Depression Inventory)
change in depression symptoms from study entrance to study exit
Time frame: study entrance to exit, an average of 12 weeks
change in anxiety symptoms (anxiety subscale; Mood and Anxiety Symptom Questionnaire)
change in anxiety symptoms from study entrance to study exit
Time frame: study entrance to exit, an average of 12 weeks
change in anhedonia symptoms (anhedonia subscale; Mood and Anxiety Symptom Questionnaire)
change in anhedonia symptoms from study entrance to study exit
Time frame: study entrance to exit, an average of 12 weeks
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