Eye Movements Recording Using a Smartphone: Comparison to Standard Video-oculography and Correlation to Imaging Data in Young Athletes

Association de Recherche Bibliographique pour les Neurosciences36 enrolled

Overview

This study aims to compare measurements obtained through the e-VOG application (mobile application, usable on smartphones or tablets, to record eye movements) with measurements from the standard video-oculography device (Eye-Tracker®T2), in young athletes. This study also aims to correlate these measurements with volumetric data from cerebral imaging (if MRI done in routine care at the same period, more or less 1 month).

e-VOG Young athletes is a collaborative study between the Memory Center of the Rainier III Center (Princess Grace Hospital, Monaco), the Neurology Department of Nice University Hospital (France), and the AS Monaco Football Academy medical team. Memory Center of the Rainier III Center is expert in eye-tracking and is equipped with a standard video-oculography device (Eye-Tracker®T2), which records eye movements at a high frequency and measures saccades parameters (latency, speed, amplitudes etc...). e-VOG is a mobile application, home-developed by the Neurology Department team of Nice University Hospital, to measure eye movements. In the continuity of the e-VOG(YA) study (NCT05211752), we set-up study named e-VOG-Young Athletes-Extension. This study will increase the number of assessments carried out (standard video-oculography assessment versus e-VOG digital assessment) in a population of athletes without major health problems, and who have not presented concussion, in order to meet more powerfully the main objective of the e-VOG(YA) study. It will also make it possible to observe whether there is a correlation between disturbed oculomotor movements, oculomotor anomalies and volumetric data measured by cerebral MRI (obtained using automatic segmentation software on cerebral regions specifically involved in the eye movement control).

Study Type

OBSERVATIONAL

Enrollment

Conditions

Healthy

Interventions

eVOG (Mobile VideoOculoGraphy)OTHER

* Eyes movements assessed with e-VOG (mobile application developed on an iPad, that uses the face detection features of the front camera to detect and record eye movements). * Study duration is about 20 minutes, the day the subject performs his standard video-oculography examination in routine care (using Eye-Tracker®T2)

Eligibility

Sex: ALLMin age: 15 YearsMax age: 19 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Young Athletes from AS Monaco Academy * referred by AS Monaco Medical Team to perform a video-oculography (Eye-Tracking) examination as part of routine care. * covered by a health insurance system * volunteer, able to give free, informed and written consent. Exclusion Criteria: * General anaesthesia within 3 months. * Head trauma within 3 months * Neurological, ophthalmological or general pathology preventing the realization of a video-oculography examination. * Oculomotor abnormality detectable on clinical examination by the neurologist prescribing the standard video-oculography examination.

Locations (1)

Centre Mémoire / Centre de Gérontologie Clinique Rainier III / Princess Grace Hospital

Monaco, Monaco

Outcomes

Primary Outcomes

Oculomotor profiles concordance

Analyze of the concordance of the profiles obtained between the e-VOG digital assessment and the standard video-oculography assessment. Evaluation criteria: For each assessment, patients will be classified according to the number of oculomotor abnormality observed (based on identified parameters assessments: latency / speed / gain / altered ocular pursuits / fixation disorders / presence of internuclear ophthalmoplegia), in accordance with the literature standards

Time frame: Day 0

Secondary Outcomes

Latency during horizontal reflex saccades

Measure of Latency during an horizontal reflex saccades paradigm with e-VOG Compared to the one performed with standard video-oculography device. Evaluation criteria: latency (reaction time in ms).

Time frame: Day 0

Latency during vertical reflex saccades

Measure of Latency during a vertical reflex saccades paradigm with e-VOG Compared to the one performed with standard video-oculography device. Evaluation criteria: latency (reaction time in ms).

Time frame: Day 0

Latency during horizontal voluntary saccades

Measure of Latency during an horizontal volontary saccades paradigm with e-VOG Compared to the one performed with standard video-oculography device. Evaluation criteria: latency (reaction time in ms).

Time frame: Day 0

Velocity during horizontal reflex saccades

Measure of Velocity during an horizontal reflex saccades paradigm with e-VOG Compared to the one performed with standard video-oculography device. Evaluation criteria: velocity (mean and peak velocity) in °/s.

Time frame: Day 0

Velocity during vertical reflex saccades

Data from ClinicalTrials.gov

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