A cross-sectional household survey with two-stage cluster-randomized sampling. This cross-sectional household survey design to recruit a random sample of households that is representative for each of the study sites. From the selected households, all consenting, household members will be included in the study. This study is funded by the UK Wellcome Trust. The grant reference number is 215604/Z/19/Z
371 households will be randomly selected from each site in Bangladesh, Cambodia, Myanmar, and Thailand. Assuming each household has an average of 4.5 members and all members will be sampled, 1500 participants will be recruited per site. This sample size allows for the overall prevalence estimation of key survey indicators with 95% confidence and 5% degree of precision. The survey components include questionnaire interview, physical examination, blood sample collection, and point of care (PoC) tests. The questionnaire interview will collect information on household characteristics, members' disability, presence or history of disease, risk factors, self-perceived quality of life, and health seeking behaviour. For women, questions about reproductive health and antenatal care, and for young children, vaccination coverage and achievement of child development goals, will also be assessed. For physical examinations, tympanic temperature, weight and height will be measured in all household members, mid-upper arm circumference in young children, and blood pressure in adults. Blood sample will be collected from all participants aged 6 months and above. Venous blood samples will be collected from participants aged 5 years and older, and dried blood spot will be collected from children under 5 years. Samples will be shipped to a central laboratory and analysed. Haemoglobin PoC will be administered to all participants. All data will be collected directly on an electronic case report form using tablets, and uploaded to an electronic database.
Study Type
OBSERVATIONAL
Enrollment
4,747
BangladeshBuilding Resources Across Communities (BRAC)
Dhaka, Bangladesh
Medical Action Myanmar (MAM)
Yangon, Burma
Cambodia Action for Health Development (AHEAD)
Battambang, Cambodia
Chiangrai Clinical Research Unit (CCRU)
Chiang Rai, Thailand
Prevalence of long-lasting antibodies (IgG) against selected causes of non-malaria febrile illnesses
Time frame: Upon enrollment
Prevalence of Plasmodium spp. by PCR
Time frame: Upon enrollment
Prevalence of chronic Hepatitis B and C
Time frame: Upon enrollment
Prevalence of selected non-communicable diseases (e.g. diabetes, chronic obstructive pulmonary diseases, stroke) according to self-reported disease history and laboratory tests
Time frame: Upon enrollment
Prevalence of reported disability
Time frame: Upon enrollment
Lifetime prevalence of reported injury or death caused by an accident
Time frame: Upon enrollment
Self-rated overall health status
Time frame: Upon enrollment
Questionnaire evaluation of health-related quality of life
Time frame: Upon enrollment
Prevalence of self-reported tobacco, alcohol, and other substitute use among the population aged 15 and above
Time frame: Upon enrollment
Prevalence of underweight and overweight, raised blood pressure and total cholesterol
Time frame: Upon enrollment
Evaluation of household wealth quartile according to self-reported household characteristics
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Time frame: Upon enrollment
Education level, marital status, and occupation
Time frame: Upon enrollment
Self-reported health-related household characteristics (e.g. household cooking fuel, source of drinking water, possession of mosquito net)
Time frame: Upon enrollment
Proportion of population self-reported having sought for medical care in the past month, and care providers visited
Time frame: Upon enrollment
Self-reported antenatal care coverage among women who have ever given birth
Time frame: Upon enrollment
Reported vaccination coverage among children < 3 years
Time frame: Upon enrollment
Prevalence of reported exclusive breast feeding among children < 5 years
Time frame: Upon enrollment
Prevalence of children aged 3-4 years who have reached early child development milestones, reported by caretaker
Time frame: Upon enrollment
Presence of self-reported symptoms or diagnosed illness besides the outcome measures of the primary objectives
Time frame: Upon enrollment
Reported illness in the last month and type of illness
Time frame: Upon enrollment
Prevalence of IgM antibodies against selected acute non-malaria causes of febrile illness
Time frame: Upon enrollment