The purpose of this study is to evaluate the drug levels of CC-92480 after coadministration with rifampin and itraconazole and the drug levels of digoxin and rosuvastatin after coadministration with CC-92480 in healthy participants.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Covance Clinical Research Unit - Dallas
Dallas, Texas, United States
Maximum observed plasma concentration (Cmax)
Time frame: Up to 2 months
Time of maximum observed plasma concentration (Tmax)
Time frame: Up to 2 months
Area under the plasma concentration-time curve from time zero to the time of the last quantifiable concentration (AUC(0-T))
Time frame: Up to 2 months
Number of participants with adverse events (AEs)
Time frame: Up to 3 months
Number of participants with physical examination findings
Time frame: Up to 3 months
Number of participants with vital sign abnormalities
Time frame: Up to 3 months
Number of participants with 12-lead electrocardiogram (ECG) abnormalities
Time frame: Up to 3 months
Number of participants with clinical laboratory abnormalities
Time frame: Up to 3 months
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Specified dose on specified days
Specified dose on specified days