The objective of the study is to find out the in-hospital clinical outcomes among Chinese Acute Ischaemic Stroke (AIS) patients, who were treated with intravenous (IV) Recombinant Tissue Plasminogen Activator (rt-PA) within 4.5 hours of symptom onset in different age groups (18 to 80 years and above 80 years).
Study Type
OBSERVATIONAL
Enrollment
113,035
Intravenous recombinant tissue plasminogen activator (IV rt-PA)
Boehringer Ingelheim (China) Investment Co., ltd.
Shanghai, China
All-cause Mortality During Hospitalization of Acute Ischemic Stroke (AIS) Patients
All-cause mortality during hospitalization of acute ischemic stroke (AIS) patients who received intravenous recombinant tissue plasminogen activator (IV rt-PA).
Time frame: Up to 100 days.
Percentage of Patients With Hemorrhagic Stroke During Hospitalization
Percentage of patients with hemorrhagic stroke during hospitalization.
Time frame: Up to 100 days.
Change of NIHSS Score From Before Intravenous Recombinant Tissue Plasminogen Activator (IV Rt-PA) Treatment to 24 Hours After IV Rt-PA Treatment
The National Institutes of Health Stroke Scale (NIHSS) is a scale of stroke severity, it ranges from 0 to 42 where a score of 0 indicates no stroke symptoms and higher scores indicate incremental levels of neurologcial impairment.
Time frame: Up to 24 hours.
Modified Rankin Score (mRS) at Discharge
The Modified Rankin Score (mRS) ranges from 0 to 6, where 0 indicates no symptoms, 1 no significant disability, 2 slight disability, 3 moderate disability, 4 moderately severe disability, 5 severe disability and 6 death.
Time frame: Up to 100 days.
Number of Patients With Stroke Recurrence During Hospitalization
Number of patients with stroke recurrence during hospitalization.
Time frame: Up to 100 days.
Length of Hospitalization
Length of hospitalization.
Time frame: Up to 100 days.
Percentage of Intravenous Recombinant Tissue Plasminogen Activator (IV Rt-PA) Treatment Among Acute Ischemic Stroke (AIS) Patients Arrived or Were Admitted to the Hospital Within 4.5 Hours of Symptom Onset
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Percentage of intravenous recombinant tissue plasminogen activator (IV rt-PA) treatment among acute ischemic stroke (AIS) patients arrived or were admitted to the hospital within 4.5 hours of symptom onset.
Time frame: Up to 4.5 hours.
Percentage of Intravenous Recombinant Tissue Plasminogen Activator (IV Rt-PA) Treatment Within 4.5 Hours of Symptom Onset Among Eligible AIS Patients (3.5-hour Arrival or Admission)
Percentage of intravenous recombinant tissue plasminogen activator (IV rt-PA) treatment within 4.5 hours of symptom onset among eligible AIS patients (3.5-hour arrival or admission).
Time frame: Up to 4.5 hours.