Respiratory and Quadriceps Muscle Fatigability After an ICU Acquired Weakness

Groupe Hospitalier du Havre20 enrolled

Overview

Muscle dysfunction can be lead to poor outcomes moreover ICU muscle weakness recovery are not correctly described. The investigators aimed to assess the ability for quadriceps or respiratory muscles to repeat an effort at a maximal loading.

Study Type

OBSERVATIONAL

Enrollment

Conditions

ICU Acquired Weakness

Interventions

Muscle evaluationDIAGNOSTIC_TEST

Repeated maximal voluntary contraction

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Mechanically ventilated at least at 24 Hours * Maximal inspiratory pressure \< 30 centimeter of water * MRC score \< 48/60 Exclusion Criteria: * Age \< 18 years * Patients with neurological pathology or pre existing neuromuscular dysfunction * Patient unable to walk 50 meters before ICU admission * Patient with a thoracic or abdominal surgery * Inability to carry out maximal voluntary contraction

Locations (1)

Groupe Hospitalier du Havre

Montivilliers, Groupe Hospitalier Du Havre, France

Outcomes

Primary Outcomes

Change in Respiratory muscle strength

Respiratory muscle strength will be assessed by Maximal Inspiratory pressure in centimeter of water. The measure will carry out by an electronical manometer

Time frame: One day

Change in quadriceps muscle strength

Quadriceps muscle strength will be assessed by Maximal Voluntary contraction of the quadriceps in Newton. The measure will carry out by an electronical dynamometer

Time frame: One day

Data from ClinicalTrials.gov

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