Nitrous oxide (commonly known as 'laughing gas') is often used during dental and other outpatient procedures, because it is easy to administer, is short-acting and rapidly clears from the body following the procedure. The investigators hypothesize that use of Nitrous oxide during GI endoscopy may enhance patient comfort during the procedure and speed-up post-procedure recovery, while minimizing the fatigue and mental fogginess some patients report the day after receiving standard sedative and narcotic drugs used routinely for the procedure. The investigators are interested in determining if adding Nitrous Oxide to commonly used sedation drugs will decrease fatigue, mental fogginess, and nausea/vomiting, as well as determine when the patient felt fully recovered from the effects of all sedatives given for the procedure.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
100
Nitrous oxide will be administered by face or nasal mask to be inhaled by the patient
Stanford University Hospital
Stanford, California, United States
RECRUITINGIntravenous sedative drug
Tabulate the types and dosages of intravenous sedative drugs given
Time frame: Duration of the procedure (1-2 hours)
Recovery time
Time spent in procedure room to recover
Time frame: Duration of the procedure (1-3hours)
Patient comfort
Patient comfort rating intra-procedure using standardized scale
Time frame: Duration of the procedure (1-3hours)
Fatigue
The number of patients who experienced fatigue
Time frame: 24-36 hours
Fatigue
The duration of fatigue experienced, if any
Time frame: 24-36 hours
Nausea/vomiting
Number of patients who experienced nausea/vomiting
Time frame: 24-36 hours
Nausea/vomiting
Duration of nausea/vomiting
Time frame: 24-36 hours
Mental Fogginess post-procedure/sedation
Duration of mental fogginess following the procedure/sedation
Time frame: 24-36 hours
Mental Fogginess post-procedure/sedation
Number of patients who experienced mental fogginess post-procedure/sedation
Time frame: 24-36 hours
Return to baseline function
Number of hours post-procedure/sedation for patient to return to baseline function
Time frame: 24-36 hours
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