Participating in regular physical activity has been shown to reduce the risk of developing some diseases and disabilities that can occur with ageing. Muscles naturally decline with age, and in females this appears to occur more so around the time of menopause. Time, work, family commitments and the availability of facilities have all been identified as barriers to exercise in middle age. Increasing activity levels in middle age appears to improve muscle function and bone health. However, there is a lack of evidence in how muscle function responds to low impact resistance exercise in middle aged females. This study aims to assess the effectiveness and the mechanisms associated with building muscle as well as the effect on quality of life in middle aged (40-60 years) females using a low impact resistance training programme.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
72
12 week supervised low impact resistance training program
12 week unsupervised low impact resistance training program
University of Exeter
Exeter, United Kingdom
Muscle function
Peak torque (Nm) of the shoulder and hip
Time frame: 12 weeks
Body composition
Changes in fat mass and lean body mass
Time frame: 12 weeks
Bone mineral density
Changes in bone mineral density
Time frame: 12 weeks
Muscle thickness
Changes in muscle thickness
Time frame: 12 weeks
Muscle protein synthesis
Rate of muscle protein synthesis
Time frame: 12 weeks
Energy expenditure
Changes in energy expenditure rates
Time frame: 12 weeks
Sleep Quality
Changes in sleep quality using the Pittsburgh sleep quality index (PSQI) questionnaire
Time frame: 12 weeks
Self reported quality of life
Changes in self reported wellbeing measures using the Short Form Survey (SF-36)
Time frame: 12 weeks
Physical activity levels
Changes in physical activity energy expenditure as measured using an accelerometer
Time frame: 12 weeks
Exercise program acceptability
Changes in the rating of enjoyment of leisure time activity using the Groningen Enjoyment Questionnaire to rate enjoyment of exercise on a scale from strongly disagree to strongly agree
Time frame: 12 weeks
Changes in balance
Balance measured using the Y-balance test
Time frame: 12 weeks
Changes in flexibility
Flexibility measured using distance (cm) in zipper and sit and reach test
Time frame: 12 weeks
Changes in cardiovascular risk markers
Changes in biochemical lipid profile
Time frame: 12 weeks
Changes in diabetes risk markers
Changes in biochemical measures of HbA1c
Time frame: 12 weeks
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