The aim of this study is to evaluate the effects of Baduanjin on blood pressure in individuals with high normal blood pressure (SBP 130-139 mmHg, and/or DBP 85-89 mmHg), as well as on glucose and lipid metabolism, quality of life, psychology, exercise, immune inflammation, endothelial function, and arterial stiffness.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
216
Participants in Baduanjin group will receive health education on hypertension and attend a 4-hour class to learn Baduanjin before receiving the interventions after the randomization. Baduanjin exercise protocol is based on the "Fitness Qigong Baduanjin Standard" enacted by the General Administration of Sports in 2003. Each Badaunjin exercise session will last at least 30 minutes and be conducted at least 5 days per week for 52 weeks. These participants will be required to practice Baduanjin regularly, and the researchers will monitor their adherence to practice and provide reminders if needed.
Participants in this group will receive health education on hypertension and practice brisk walking on their own for at least 30 minutes, at least 5 days per week for 52 weeks. These participants will be required to do brisk walking regularly, and the researcher will monitor their adherence to practice and provide reminders if needed.
Fuwai Hospital
Beijing, Beijing Municipality, China
Change from baseline ambulatory 24-h systolic blood pressure (mmHg) at 12 week
Change form Baseline ambulatory 24-h systolic blood pressure at 12 week will be measured by ambulatory blood pressure monitoring to investigate the short-term antihypertensive effect of Baduanjin.
Time frame: Baseline, 12 week
Change from baseline ambulatory 24-h systolic blood pressure (mmHg) at 52 week
Change from baseline ambulatory 24-h systolic blood pressure at 52 week will be measured by ambulatory blood pressure monitoring to investigate the long-term antihypertensive effect of Baduanjin.
Time frame: Baseline, 52 week
Other blood pressure indicators: daytime mean SBP(mmHg), nighttime mean SBP(mmHg), 24-h DBP(mmHg), daytime mean DBP(mmHg), nighttime mean DBP(mmHg)
Other blood pressure indicators:daytime mean systolic blood pressure, nighttime mean systolic blood pressure, 24-h diastolic blood pressure, daytime mean diastolic blood pressure, nighttime mean diastolic blood pressure
Time frame: Baseline,12 week,52 week
SBP(mmHg)
Blood pressure indicator:office systolic blood pressure
Time frame: Baseline,4 week,8 week,12 weeks,24 week,32 week,52 week
DBP(mmHg）
Blood pressure indicator:office diastolic blood pressure
Time frame: Baseline,4 week,8 week,12 weeks,24 week,32 week,52 week
FBG(mmol/L)
Glucose metabolism indicator: fasting blood glucose
Time frame: Baseline,12 week,52 week
HbA1c(%)
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Glucose metabolism indicator: hemoglobin A1c
Time frame: Baseline,12 week,52 week
Insulin
Glucose metabolism indicator
Time frame: Baseline,12 week,52 week
C-peptide
Glucose metabolism indicator
Time frame: Baseline,12 week,52 week
Lipid metabolism parameters: TC(mmol/L), TG(mmol/L), HDL-C(mmol/L), LDL-C(mmol/L)
Lipid metabolism indicators: total cholesterol , triglyceride , high density lipoprotein cholesterol, low density lipoprotein cholesterol
Time frame: Baseline,12 week,52 week
Total scores of The Short-Form-36 Health Survey (SF-36)
The total scores range from 0-100, and the higher scores mean better outcomes
Time frame: Baseline,12 week,52 week
Total scores of Pittsburgh Sleep Quality Index(PSQI)
The total scores range from 0-21, and the higher scores mean worse outcomes
Time frame: Baseline,12 week,52 week
Total scores of Generalized Anxiety Disorder-7(GAD-7)
The total scores range from 0-21, and the higher scores mean worse outcomes
Time frame: Baseline,12 week,52 week
Total scores of Patient Health Questionnaire-9 items(PHQ-9)
The total scores range from 0-27 , and the higher scores mean worse outcomes
Time frame: Baseline,12 week,52 week
Total scores of Neck Disability Index(NDI)
The total scores range from 0-100%, and the higher scores mean worse outcomes
Time frame: Baseline,12 week,52 week
Sit and reach test(cm)
Motor system function: sit and reach test
Time frame: Baseline,12 week,52 week