Clinical Efficacy of Ginkgo Biloba Extract in the Treatment of Knee Osteoarthritis

Inclusion Criteria: * patients 40-75 years old with knee OA. * Grade II and Grade III according to the Kellgrenn-Lawrence (KL) grading system of radiographic OA. Exclusion Criteria: * Pregnancy, breastfeeding * Liver or renal problems * Patient taking any drug that might interact with Ginkgo extract (eg. warfarin, etc.) * patient with cardiovascular or cerebral vascular disorders, uncontrolled diabetes, allergic to ginkgo, recent surgery or hospital admission, \>75 years old. * Allergic or contraindicated to using NSAIDs