The aim of the present study is to evaluate the use of probiotics in domiciliary oral hygiene procedures in pregnant women. Patients consenting to participate to the study will undergo periodontal evaluation at the baseline (T0). Then, professional dental hygiene will be performed. Patients will be randomly assigned to: * Trial group: home oral application of Biorepair Peribioma Toothpaste + Biorepair Peribioma mousse twice a day * Control group: home oral application of Biorepair Peribioma Toothpaste Patients will be evaluated after 1 month (T1), 3 (T2) and 6 (T3) months.
The aim of the present study is to evaluate the use of probiotics in domiciliary oral hygiene procedures in pregnant women. Patients consenting to participate to the study will undergo periodontal evaluation at the baseline (T0). Then, professional dental hygiene will be performed. Patients will be randomly assigned to: * Trial group: home oral application of Biorepair Peribioma Toothpaste + Biorepair Peribioma mousse twice a day * Control group: home oral application of Biorepair Peribioma Toothpaste Patients will be evaluated after 1 month (T1), 3 (T2) and 6 (T3) months, the following indexes will be assessed: Probing Pocket Depth, Bleeding on Probing (percentage), Clinical Attachment Loss, Gingival recession, Plaque Control Record, Modified Gingival Index, Papillary Marginal Gingival Index.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
30
Domiciliary application of the products twice a day.
Domiciliary application of the product twice a day.
Unit of Dental Hygiene - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Paediatrics - University of Pavia
Pavia, Lombardy, Italy
Change in PPD - Probing Pocket Depth
Evaluation (in mm) of the depth of the gingival sulcus, through a millimeter periodontal probe; it is detected from the gingival margin to the bottom of the gingival sulcus or periodontal pocket, evaluated at 6 sites.
Time frame: Baseline, after 1, 3 and 6 months.
Change in BOP - Bleeding on Probing (percentage)
Site-specific assessment of the presence or absence of gum bleeding after the insertion of the periodontal probe for the detection of PPD, detected on 6 sites. Percentage of sites with bleeding on probing determines the BOP%.
Time frame: Baseline, after 1, 3 and 6 months.
Change in CAL - Clinical Attachment Loss
Measurement (in mm) of the position of the gingival margin in relation to the cemento-enamel junction (CEJ).
Time frame: Baseline, after 1, 3 and 6 months.
Change in R - Gingival recession
Distance (in mm) between the gingival margin and the amelo-cemental junction.
Time frame: Baseline, after 1, 3 and 6 months.
Change in PCR% - Plaque Control Record
% assessment of the amount of plaque on dental surfaces; it is detected on 4 surfaces: distal, mesial, vestibular, lingual / palatal. The number of sites with plaque is divided by the total number of sites available in the mouth and multiplied by 100. Results indicate the index as a percentage.
Time frame: Baseline, after 1, 3 and 6 months.
Change in MGI - Modified Gingival Index
Scoring criteria: * 0: normal * 1: mild inflammation (slight changes in color and texture, but not in all portions of gingival marginal or papillary) * 2: mild inflammation (slight changes in color and texture in all portions of gingival marginal or papillary) * 3: moderate (bright surface inflammation, erythema, edema, and/or hypertrophy of gingival marginal or papillary) * 4: severe inflammation (erythema, edema, and/or marginal gingival hypertrophy of the unit or spontaneous bleeding, papillary, congestion, or ulceration)
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Time frame: Baseline, after 1, 3 and 6 months.
Change in PMGI - Papillary Marginal Gingival Index
Numerical score from 0 to 3 of gingival inflammation. Papille and gingival margins (vestibular and lingual) are given a score from 0 to 3. The score is given by the total amount of inflamed sites on the total of examined sites.
Time frame: Baseline, after 1, 3 and 6 months.