Brimonidine in Rosacea

Cairo University45 enrolled

Overview

Rosacea is a chronic and relapsing inflammatory cutaneous disorder with highly variable prevalence worldwide.

In our study, we will compare the safety, efficacy, and adverse effects of low-dose oral doxycycline alone versus combined with pulsed dye laser or topical brimonidine in treating erythematotelangiectatic rosacea in an attempt to build a treatment strategy in a disease with complex pathogenesis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Rosacea

Interventions

treatmentOTHER

types

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient with current erythematotelangiectatic rosacea Exclusion Criteria: \- Pregnant females. 2-Patients on systemic steroids. 3-Patients complaining of other dermatological disorders mainly photosensitive cutaneous disorder. 4- Patients receiving any systemic treatment including retinoids for the previous 1 month or any topical treatment for the previous 2 weeks or any laser sessions for the previous 3months for erythematotelangiectatic rosacea at least.

Outcomes

Primary Outcomes

Clinical erythema assessment scale

clinical scale

Time frame: 3 months

Secondary Outcomes

Thickness of capillaries by dermoscope

Assessment

Time frame: 3 months

Data from ClinicalTrials.gov

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