On the basis of previous studies, a validation cohort will be established to explore the relationship between oral lichen planus and autoimmune thyroid diseases, and a disease efficacy prediction strategy can be formed.
For oral lichen planus patients, the prevalence of Hashimoto's thyroiditis will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined. Besides, for patients with Hashimoto's thyroiditis, the prevalence of oral lichen planus will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined.
Study Type
OBSERVATIONAL
Enrollment
150
The Stomatology Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
Oral lichen planus (OLP) lesions record
Record changes of lesions based on the symptoms and signs of the oral lichen planus patient.
Time frame: 1 year
Level of thyroid function and antibody
The levels of thyroid hormone and thyroid autoantibodies in serum of OLP patients were detected.
Time frame: 1 year
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