This study is aim to disclose the effect of contrast media, which used in epidural steroid injections, on the parameters of thyroid function tests (TFTs). The patients who underwent an epidural steroid injection were included. The investigators hypothesized that contrast media owing to contain iodine may impair the values of TFTs.
The objective of this study is to reveal the impact of contrast media, whether they change the values of TFTs in participants who had been performed any kind of epidural steroid injection such as Lumbar, cervical and caudal epidural steroid injection. The inclusion criteria were participants who had normal values of TFTs, being between the ages of 18 and 65 and had an epidural steroid injection. Patients with impaired parameters of TFTs or had thyroid surgery, systemic and/or local infections, malignancy, bleeding diathesis, acute fracture, known allergy to contrast material and/or local anesthetic substances, known history of any psychiatric disorder, and patients with a history of pregnancy were excluded from the study. Verbal and written informed consent was obtained from all patients participating in the study. In conjunction with the recording of the demographic data of the patients participating in this study (age, sex, duration of symptoms, etc.), their contrast medium doses and the values of TFTs (free T3, free T4 and Thyroid-stimulating hormone) were employed before the procedure and 3rd week after the procedure.
Study Type
OBSERVATIONAL
Enrollment
124
This intervention is applied mostly for cervical or lumbar radiculopathy. The intervention was carried out under sterile conditions with the C-arm fluoroscopy guidance. It is performed via spinal needle and the needle is inserted into the epidural space, then a combined local anesthetic and glucocorticoids are delivered to the epidural space.
Marmara University Pendik Training and Research Hospital
Istanbul, Pendik, Turkey (Türkiye)
The Values of free T4
Free T4 is a type of thyroid hormone. A free T4 test is used to evaluate thyroid function
Time frame: Change of the values of free T4 from baseline to each checkpoints from pre-interventional time to postinterventional 3rd week
The Values of free T3
The free T3 is an another major hormone of the thyroid gland. It is used to show thyroid functions.
Time frame: Change of the values of free T3 from baseline to each checkpoints from pre-interventional time to postinterventional 3rd week
The Values of Thyroid-stimülating hormone (TSH)
TSH is secreted from the pituitary gland to stimulate the thyroid gland. It regulates thyroid functions. This test is also used for thyroid functions.
Time frame: Change of the values of TSH from baseline to each checkpoints from pre-interventional time to postinterventional 3rd week
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.