To Evaluate Pharmacokinetics (PK) and Safety of Tavapadon in Participants With Severe Renal Impairment Compared to Participants With Normal Renal Function

Key Inclusion Criteria: 1. Body mass index of ≥18.0 to 40.0 kilograms per meter square (kg/m\^2), inclusive, and a total body weight \>50 kilograms (kg) \[(110 pounds (lbs)\]. 2. Age that is within ±10 years of the median age for the severe renal impairment cohort. Bodyweight that is within ±15 kg of the median bodyweight for the severe renal impairment cohort. 3. Severe renal function: estimated glomerular filtration rate (eGFR) \<30 mL/min (not requiring dialysis) determined using Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. 4. Stable disease, defined as no clinically significant changes in disease status as documented by the most recent eGFR assessment (within at least 3 months before Screening). 5. Stable concomitant medications for the management of individual participants medical history. Key Exclusion Criteria: 1. Serious risk of suicide in the opinion of the investigator. 2. History of substance or alcohol use disorder (excluding nicotine or caffeine) within 12 months prior to signing the informed consent form (ICF). 3. Receipt of severe acute respiratory syndrome coronavirus 2(SARS-CoV2) vaccine or booster within 7 days of planned dosing. 4. Have recently been diagnosed with symptomatic Coronavirus Disease 2019 (COVID-19) or test positive for COVID-19 within 30 days prior to signing the ICF. 5. Positive drug screen including tetrahydrocannabinol (THC). 6. Positive result for human immunodeficiency virus (HIV) antibody, hepatitis B surface antigen, hepatitis B core antibody, or hepatitis C antibody with detectable viral ribonucleic acid (RNA) levels at Screening. 7. Positive drug screen including THC (except with a vail prescription other than medical marijuana). 8. Participants who have received an organ transplant or are currently waiting for an organ transplant and are listed on the national transplant list. 9. Participants who require dialysis. 10. Participant with nephrotic syndrome. 11. Abnormal hemoglobin. 12. Abnormal blood pressure measurement or heart rate at Screening or Check-in. Note: Other protocol defined Inclusion/Exclusion criteria may apply.