The main purpose of this observation study is to collect data on the effects and side effects for 12 weeks of the medication administration of the single-pill combinations, which are fimasartan/amlodipine or fimasartan/amlodipine/hydrochlorothiazide, based on fimasartan. (Stage 1). Also, this study will evaluate major cardiovascular events, long-term blood pressure control, and the safety by follow-up of those who consent to the extended study for about 2 years (96 weeks).(Stage 2)
This study will be conducted as a prospective observational study in about 600 domestic medical institutions, which are at least clinical level. The investigator will enroll those who have essential hypertension and meet the inclusion and exclusion criteria after obtaining voluntary written consent for participation in the study and use of personal information. This study is a non-interventional observational study and is based on decisions by the investigator about the choice of antihypertensive drugs, the period of treatment, and the medication change status etc. During this study period, the scope of data to be collected is as follows: * Demographic information * Disease information (historical diseases and concomitant diseases ) * Physical measurements and vital signs * Blood pressure Central Blood pressure and hemodynamic values (if applicable) * Information on antihypertensive drugs and other concomitant medications * Adverse drug reaction(ADR) and serious adverse drug reactions(SADR) related to fimasartan/amlodipine or fimasartan/amlodipine/hydrochlorothiazide * Information on cardiovascular events (Only if subjects are in long term follow-up) * Death information (Only if subjects are in long term follow-up)
Study Type
OBSERVATIONAL
Enrollment
20,000
Seoul National University Bundang Hospital
Seoul, South Korea
RECRUITINGThe blood pressure control rate
The blood pressure control rate (\< 140/90 mmHg)(Systolic and Diastolic) at Week 12
Time frame: Week 12
The blood pressure control rate
The blood pressure control rate (\< 140/90 mmHg) at Week 8
Time frame: Week 8
The target blood pressure control rate
The target blood pressure control rate (\< 140/90 mmHg) at Week 12
Time frame: Week 12
Change in central systolic pressure(CSP) and Central diastolic pressure(CDP)
Change in central systolic pressure(CSP) and Central diastolic pressure(CDP) at Week 12 from baseline (Only the subjects who measured the central blood pressure)
Time frame: Week 12
Control rate of The Blood pressure control rate
Control rate of The Blood pressure control rate(\< 140/90 mmHg) at Week 36 , 48 and 96
Time frame: Week 36, Week 48, Week 96
The target blood pressure control rate
The target blood pressure control rate at Week 36 , 48 and 96
Time frame: Week 36, Week 48, Week 96
The incidence rate of major cardiovascular event(MACE)
The incidence rate of major cardiovascular event(MACE)
Time frame: Week 96
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.