Assessment of the Effects on the Skin Microbiome of Amending an Over-the-counter Eczema Product With Activated Oil (AO)

Inclusion Criteria: * Provision of signed and dated informed consent form. * Stated willingness to comply with all study procedures and availability for the duration of the study. * Male or female subjects aged who have a recent eczema itch flareup and/or pre-flare-up symptoms at screening as determined by visual analog scale (VAS). * Diagnosis of mild to moderate eczema (grade 3 - 7 on the Rajka-Langeland severity index). * Having a target lesion with an ADSI score of 6-12 and an erythema and pruritus subscore of ³2 (moderate). * Generally good health based on reported history. * Able to discontinue all medical and over the counter topical emollients, moisturizers, and / or other skin barrier lotions. * Females of child-bearing potential should agree to continue using a medically acceptable method of birth control throughout the study and for 30 days immediately after the last dose of study drug. * Ability to administer topical medication and be willing to adhere to the study interventions. * Agreement to adhere to Lifestyle Considerations throughout the duration of the study. Exclusion Criteria: * Pregnancy or lactation. * Any type of malignancy involving the Study Site Area (Lesion or Non-Lesion site) in the last 5 years. * Known allergy to hydrocortisone or topical antibiotic. * Topical or oral use of an antibiotic within the last 7 days prior to baseline clinical visit. * Bleach bathing in the 7 days prior to Baseline clinical visit. * Current use of Class I-III topical corticosteroids or systemic medications (e.g. Dupixent) potentially affecting eczema or the skin. * Surgeries or invasive medical procedures planned during course of study. * Suspected non-compliance or non-cooperation. * Intake of experimental drugs or experimental topical skin treatments within 30 days prior to study start. * Mental disability or any other lack of fitness, in the Investigator's opinion, to preclude subject's participation in or ability to complete the study. * Diagnosis of human immunodeficiency virus in medical history.