Prostatic Artery Embolization for the Treatment of Lower Urinary Tract Symptoms in Prostate Cancer Patients Undergoing Radiation Therapy

Inclusion Criteria: * Age ≥ 40 years and ≤ 90 years old * Prostate volume ≥ 40 mL and ≤ 300 mL * Biopsy proven prostate cancer undergoing radiation therapy * Diagnosis of moderate to severe lower urinary tract symptoms (LUTS) defined as at least one of the following: 1. IPSS ≥ 12 or dependent on urinary catheterization, or 2. IPSS Quality of Life (QoL) assessment ≥ 3, and 3. Qmax ≤ 12 mL/sec * Ability to understand and willingness to sign the written consent Exclusion Criteria: * Neurogenic bladder disorder due to multiple sclerosis, Parkinson's disease, spinal cord injury, diabetes, etc., as demonstrated on urodynamic testing. * Detrusor muscle failure, urethral stenosis, or urinary obstruction due to causes other than prostatic obstruction, as demonstrated on urodynamic testing * Bladder diverticula greater than 5 cm or bladder stones greater than 2 cm * Other active urogenital cancer * Baseline serum creatinine greater than 2 mg/dL * Evidence of tortuous or atherosclerotic blood vessels * Coagulation disturbances not normalized by medical treatment * Allergy to iodinated contrast agents not responsive to steroid premedication regimen