Hantavirus Nephropathy in North-Eastern France : Severity Risk Factors and Prognostic Tools

Score performance to predict severity

Correlation between severity predicted by the score and bio-clinical severity during hospitalization. Score composition : Hematuria = 7 Visual disorders = 8 Leucocyte count \> 10 x 10\^9 cells/L = 9 Nephrotoxic drug exposure (NSAID, iodinated contrast media, diuretics, renin angiotensin aldosterone system inhibitors, aminoglycosides, glycopeptides) = 10 Thrombocytopenia \< or = 90 000/mm3 = 11 Risk group according score scale 0-10 Low risk 11-19 intermediate risk 20-45 high risk

Time frame: Through study completion, an average of 2 years

Hypotension

Lowest systolic blood presure during hospitalisation \< 90mmHg

Time frame: Through study completion, an average of 2 years

Proteinuria

Proteinuria during hospitalisation defined by proteinuria/creatininuria above 500 mg/g or equivalent

Time frame: Through study completion,an average of 2 years

Urinary dipstick

Leucocyturia or hematuria

Time frame: Through study completion, an average of 2 years

ALAT, ASAT

Liver cytolysis

Time frame: Through study completion, an average of 2 years

calcium

hypocalcemia, hypercalcemia

Time frame: Through study completion, an average of 2 years

phosphorus

hypophaspahtaemia, hyperphasphatemia

Time frame: Through study completion, an average of 2 years

potassium

hypokaliemia, hyperkaliemia

Time frame: Through study completion, an average of 2 years

sodium

blood sodium level disorders

Time frame: Through study completion, an average of 2 years

bicarbonate blood level

metabolic acidosis, metabolic alcalosis

Time frame: Through study completion, an average of 2 years

Heamoglobin

Anemia

Time frame: Through study completion, an average of 2 years

platelets level

thrombocytemia

Time frame: Through study completion, an average of 2 years

Urine output

Polyruria above 3 L/day

Time frame: Through study completion, an average of 2 years