A Trail of Drug-coated Balloon Treating Below The Knee Arterial Diseases

Inclusion Criteria: * Age 18-85 years； * ≥70% diameter stenosis or occlusion in the target below-the-knee lesion； * Rutherford Category 3-6； * Subjects are willing to sign informed consent； Exclusion Criteria: * Planned major limb amputation within 30 days after the procedure; * In-stent stenosis in the target lesion; * Severely calcified target lesions； * Creatinine\>2.5mg/dL; * History of allergies to anesthetics, contrast agents； * Subjects who have participated in any other drug or medical device clinical investigations and haven't reach the primary endpoint； * Other circumstances judged by researchers that are not suitable for enrollment.