Safety and Efficacy of a Probiotic Supplement

Inclusion Criteria: * Males, females between 18-50 years of age * Healthy and injury free as determined by screening questions and medical history * Distance runners as determined by physical activity questionnaire; run = 15 miles/week, run = 3 time or more/week * VO2max level of = 40ml/kg/min for males or = 35ml/kg/min for females * Agree to maintain normal diet and exercise routine throughout study * Agrees to collect stool samples as needed * Agree to complete questionnaires, records Exclusion Criteria: * Women who are pregnant or breastfeeding, or plan to become pregnant during course of the study will not be included as the effect of probiotic on pregnancy and lactation is not established. * Subjects with a known allergy to the test material (active and placebo) * Subjects taking NSAIDs, Metformin, probiotics, or supplements that might alter the gut microbiome;these will be assessed individually. (Multivitamin and protein supplementation are allowed) * Subject that have abnormal test results during screening. * Alcohol or drug abuse within past year (alcohol can impair gut barrier). * History of GI surgery within past year as it would alter the gut microbiome (excluding appendectomy and herniorrhaphy). * Severe heart, liver, kidney, neurological, oncological or psychiatric disease, or immunosuppressed subjects will be excluded. * Coeliac disease, inflammatory bowel disease or acute pancreatitis (all 3 can impair gut barrier) * Regular use of antacid medication (can significantly alter microbiota) * Subject following a low FODMAP (fermentable oligo-, di-, mono-saccharides and polyols) diet will be excluded as this dietary pattern can alter the intestinal response to exercise in some people.