Comparing Two Indirect Pulp Capping Agents for Permanent Teeth

Cairo University30 enrolled

Overview

Aim of the study: To evaluate clinical and radiographic success rates of silver diamine fluoride versus mineral trioxide aggregate as indirect pulp capping agents in deeply carious young first permanent molars.

Indirect pulp treatment has become a common maneuver in vital pulp therapy in recent years and is a procedure performed in teeth with deep carious lesions approximating the pulp but without any signs or symptoms of irreversible pulpal changes. Silver Diamine Fluoride is used to arrest caries lesions in primary teeth but according to the AAPD,2021 more research is needed on the use of SDF to arrest caries lesions in permanent teeth.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Deep Caries

Interventions

Silver diamine fluorideDRUG

First permanent molars in this group will receive 38% silver diamine fluoride as an indirect pulp capping material.

Mineral trioxide aggregateDRUG

First permanent molars in this group will receive mineral trioxide aggregate as an indirect pulp capping material.

Eligibility

Sex: ALLMin age: 9 YearsMax age: 14 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient and parent showing cooperation and compliance. * Children 9-14 years old * Vital deeply carious young first permanent molar(s) with complete root formation * Asymptomatic teeth or without clinical symptoms of spontaneous pain * Both genders will be included. Exclusion Criteria: * Children unable to return for recall visits. * Any clinical signs of irreversible pulpitis or pulp necrosis (spontaneous pain, pain on percussion, abscess, sinus). * Any radiographic sign of irreversible pulp pathologies or pulp necrosis (periapical radiolucency, internal or external root resorption)

Outcomes

Primary Outcomes

Dentin bridge formation

Dentin bridge formation will be measured in millimeters on standardized digital radiographs taken by Digital Radiographic examination

Time frame: 6 months

Secondary Outcomes

Postoperative pain

Postoperative pain will be assessed by questioning the patient or the guardian whether there is postoperative pain or not, Binary (yes or no)

Time frame: 1 week

Absence of sinus or fistula

Intraoral Visual examination will be carried out to assess if there is a sinus or fistula, Binary (present/absent)

Time frame: 3 months

Absence of sinus or fistula

Intraoral Visual examination will be carried out to assess if there is a sinus or fistula, Binary (present/absent)

Time frame: 6 months

radiographic success

Absence of any adverse radiographic findings (Periodontal membrane space widening, bone resorption, pulp stones will be assessed if present or absent by digital radiographic examination, Binary (present or absent)

Time frame: 6 months

Central Contacts

Marwa Ahmed Ahmed Zaghloul

CONTACT

+201002798304 marwa_zaghloul@dentistry.cu.edu.eg

Randa Youssef Abd Al Gawad

CONTACT

randa.youssef@dentistry.cu.edu.eg

Data from ClinicalTrials.gov

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