The aim of the study is to examine the incremental value of using magnetic resonance imaging (MRI) in addition to computed tomography (CT) in the diagnostic workup of pancreatic cancer patients.
The aim of the study is to examine the incremental value of using magnetic resonance imaging (MRI) in addition to computed tomography (CT) in the diagnostic workup of pancreatic cancer patients. We will conduct a nationwide, prospective clinical trial to examine the incremental value of using MRI for identification of liver metastases in pancreatic cancer patients.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
200
Preoperative MRI performed between outpatient visit at the surgical clinic and scheduled date of resection
Aalborg University Hospital
Aalborg, Denmark
RECRUITINGAarhus University Hospital
Aarhus, Denmark
RECRUITINGRigshospitalet
Copenhagen, Denmark
RECRUITINGChange in treatment strategy
Change in treatment strategy from intended curative resection to other treatment based on MRI scan
Time frame: 1 week
Liver metastases
Proportion of patients who had liver metastases detected on MRI
Time frame: 1 week
Surgery
Proportion of patients who made it to surgery/exploration
Time frame: 1 month
Resection
Proportion of patients in each arm who had a pancreatic resection performed
Time frame: 1 month
Intraoperatively detected liver metastases
Proportion of patients with intraoperatively detected liver metastases not seen on either CT or MRI.
Time frame: 1 month
Overall survival (1-year)
1-year overall survival.
Time frame: 1 year
Overall survival (3-year)
3-year overall survival.
Time frame: 3 years
Recurrence-free survival
Recurrence-free survival according to final treatment strategy.
Time frame: 3 years
Healthcare costs
Healthcare costs in patients with change of treatment.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: 3 years